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Post Menopausal Tests - Detail
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Expanded Post Menopausal Panel
Expanded Post Menopausal Panel - ePHP1
The ePHP1 is the new generation of saliva tests. It includes the 6 hormones
of the PHP1 plus FSH and LH measurements. Clinical applications are the
same as PHP1.
Salivary LH &FSH The new generation of saliva tests for LH & FSH developed
at Diagnos-Techs allows measurements 100-1000x more sensitive than routine
serum/blood tests. By coupling levels of FSH to E2 and LH to P1, the sensitivity
of the ovary to the gonadotropins can be objectively evaluated. As a woman
approaches menopause, FSH and LH requirements to illicit the same E2 and
P1, responses become higher. This relation has predictive diagnostic implications
(see figure A on following page). It allows earlier intervention before
clinical symptoms become evident.
Bone loss concerns can be addressed predictively. Pro-active nutritional,
hormonal, and therapeutic strategies can be tailored to each womans need.
Furthermore, as the FSH/E2 and LH/P1 relations change with time, therapeutic
modifications that reflect the changing needs are implemented. The FSH
and LH measurements also allow detection of microadenomas of the pituitary
gland.
It is worth noting that stress (increased cortisol and ACTH) has significant
adverse effects on LH and P1 production but minimal effects on FSH and
E2. The imbalance induced by stress can lead to estrogen dominance with
its proliferative statesFibroid and breast cyst growths, endometriosis
aggravation, edometrical hypertrophy, etc.
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